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SENP1 promotes MCL pathogenesis through regulating JAK-STAT5 pathway and SOCS2 expression

Mantle cell lymphoma (MCL) is highly aggressive and its treatment remains challenging, understanding its pathogenesis is critical for future targeted therapy. SUMO specific proteases 1 (SENP1) is an important protein that regulates the balance between SUMOylation and deSUMOylation. We found that SEN...

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Detalhes bibliográficos
Publicado no:Cell Death Discov
Main Authors: Zhang, Yali, Ma, Yanni, Wu, Guixian, Xie, Mingling, Luo, Chengxin, Huang, Xiangtao, Tian, Feng, Chen, Jieping, Li, Xi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8313533/
https://ncbi.nlm.nih.gov/pubmed/34312374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-021-00578-x
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