Targeting PML in triple negative breast cancer elicits growth suppression and senescence

Oncogene addiction postulates that the survival and growth of certain tumor cells is dependent upon the activity of one oncogene, despite their multiple genetic and epigenetic abnormalities. This phenomenon provides a foundation for molecular targeted therapy and a rationale for oncogene-based strat...

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Bibliografske podrobnosti
izdano v:Cell Death Differ
Main Authors: Arreal, Leire, Piva, Marco, Fernández, Sonia, Revandkar, Ajinkya, Schaub- Clerigué, Ariane, Villanueva, Josep, Zabala-Letona, Amaia, Pujana, Mikel, Astobiza, Ianire, Cortazar, Ana Rosa, Hermanova, Ivana, Bozal-Basterra, Laura, Arruabarrena-Aristorena, Amaia, Crespo, Jana R., Valcarcel-Jimenez, Lorea, Zúñiga-García, Patricia, Canals, Francesc, Torrano, Veronica, Barrio, Rosa, Sutherland, James D., Alimonti, Andrea, Martin-Martin, Natalia, Carracedo, Arkaitz
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7104349/
https://ncbi.nlm.nih.gov/pubmed/31570853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-019-0407-5
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