Integrative analysis of transcriptomics and clinical data uncovers the tumor-suppressive activity of MITF in prostate cancer

The dysregulation of gene expression is an enabling hallmark of cancer. Computational analysis of transcriptomics data from human cancer specimens, complemented with exhaustive clinical annotation, provides an opportunity to identify core regulators of the tumorigenic process. Here we exploit well-a...

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Gepubliceerd in:Cell Death Dis
Hoofdauteurs: Valcarcel-Jimenez, Lorea, Macchia, Alice, Martín-Martín, Natalia, Cortazar, Ana Rosa, Schaub-Clerigué, Ariane, Pujana-Vaquerizo, Mikel, Fernández-Ruiz, Sonia, Lacasa-Viscasillas, Isabel, Santos-Martin, Aida, Loizaga-Iriarte, Ana, Unda-Urzaiz, Miguel, Hermanova, Ivana, Astobiza, Ianire, Graupera, Mariona, Starkova, Julia, Sutherland, James, Barrio, Rosa, Aransay, Ana M., Carracedo, Arkaitz, Torrano, Verónica
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6181952/
https://ncbi.nlm.nih.gov/pubmed/30310055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1096-6
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