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Integrative analysis of transcriptomics and clinical data uncovers the tumor-suppressive activity of MITF in prostate cancer

The dysregulation of gene expression is an enabling hallmark of cancer. Computational analysis of transcriptomics data from human cancer specimens, complemented with exhaustive clinical annotation, provides an opportunity to identify core regulators of the tumorigenic process. Here we exploit well-a...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Valcarcel-Jimenez, Lorea, Macchia, Alice, Martín-Martín, Natalia, Cortazar, Ana Rosa, Schaub-Clerigué, Ariane, Pujana-Vaquerizo, Mikel, Fernández-Ruiz, Sonia, Lacasa-Viscasillas, Isabel, Santos-Martin, Aida, Loizaga-Iriarte, Ana, Unda-Urzaiz, Miguel, Hermanova, Ivana, Astobiza, Ianire, Graupera, Mariona, Starkova, Julia, Sutherland, James, Barrio, Rosa, Aransay, Ana M., Carracedo, Arkaitz, Torrano, Verónica
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6181952/
https://ncbi.nlm.nih.gov/pubmed/30310055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1096-6
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