Employing 25-Residue Docking Motifs from Modular Polyketide Synthases as Orthogonal Protein Connectors

The proteins of trans-acyltransferase modular polyketide synthases (PKSs) self-organize into assembly lines, enabling the multienzyme biosynthesis of complex organic molecules. Docking domains comprised of ~25 residues at the C- and N-termini of these polypeptides ((C)DDs and (N)DDs) help drive this...

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Publié dans:ACS Synth Biol
Auteurs principaux: Meinke, Jessica L., Simon, Anna J., Wagner, Drew T., Morrow, Barrett R., You, Shaochen, Ellington, Andrew D., Keatinge-Clay, Adrian T.
Format: Artigo
Langue:Inglês
Publié: 2019
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7102495/
https://ncbi.nlm.nih.gov/pubmed/31469555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acssynbio.9b00047
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