Structural basis for the increased processivity of D-family DNA polymerases in complex with PCNA

Replicative DNA polymerases (DNAPs) have evolved the ability to copy the genome with high processivity and fidelity. In Eukarya and Archaea, the processivity of replicative DNAPs is greatly enhanced by its binding to the proliferative cell nuclear antigen (PCNA) that encircles the DNA. We determined...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Madru, Clément, Henneke, Ghislaine, Raia, Pierre, Hugonneau-Beaufet, Inès, Pehau-Arnaudet, Gérard, England, Patrick, Lindahl, Erik, Delarue, Marc, Carroni, Marta, Sauguet, Ludovic
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7101311/
https://ncbi.nlm.nih.gov/pubmed/32221299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15392-9
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