Structure of the DP1–DP2 PolD complex bound with DNA and its implications for the evolutionary history of DNA and RNA polymerases

PolD is an archaeal replicative DNA polymerase (DNAP) made of a proofreading exonuclease subunit (DP1) and a larger polymerase catalytic subunit (DP2). Recently, we reported the individual crystal structures of the DP1 and DP2 catalytic cores, thereby revealing that PolD is an atypical DNAP that has...

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Detalhes bibliográficos
Publicado no:PLoS Biol
Main Authors: Raia, Pierre, Carroni, Marta, Henry, Etienne, Pehau-Arnaudet, Gérard, Brûlé, Sébastien, Béguin, Pierre, Henneke, Ghislaine, Lindahl, Erik, Delarue, Marc, Sauguet, Ludovic
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355029/
https://ncbi.nlm.nih.gov/pubmed/30657780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000122
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