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Characterization of Mycobacterium smegmatis PolD2 and PolD1 as RNA/DNA polymerases homologous to the POL domain of bacterial DNA ligase D

Mycobacteria exploit nonhomologous end-joining (NHEJ) to repair DNA double-strand breaks. The core NHEJ machinery comprises the homodimeric DNA end-binding protein Ku and DNA ligase D (LigD), a modular enzyme composed of a C-terminal ATP-dependent ligase domain (LIG), a central 3’-phosphoesterase do...

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Bibliografski detalji
Glavni autori: Zhu, Hui, Bhattarai, Hitesh, Yan, Han-Guang, Shuman, Stewart, Glickman, Michael S.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3766730/
https://ncbi.nlm.nih.gov/pubmed/23198659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi301202e
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