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Distinctive effects of domain deletions on the manganese-dependent DNA polymerase and DNA phosphorylase activities of Mycobacterium smegmatis polynucleotide phosphorylase

Polynucleotide phosphorylase (PNPase) plays synthetic and degradative roles in bacterial RNA metabolism; it is also suggested to participate in bacterial DNA transactions. Here we characterize and compare the RNA and DNA modifying activities of Mycobacterium smegmatis PNPase. The full-length (763-aa...

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Bibliografski detalji
Glavni autori: Unciuleac, Mihaela-Carmen, Shuman, Stewart
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3689434/
https://ncbi.nlm.nih.gov/pubmed/23560592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400281w
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