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Structure and mechanism of Mycobacterium smegmatis polynucleotide phosphorylase
Polynucleotide phosphorylase (PNPase) catalyzes stepwise phosphorolysis of the 3′-terminal phosphodiesters of RNA chains to yield nucleoside diphosphate products. In the reverse reaction, PNPase acts as a polymerase, using NDPs as substrates to add NMPs to the 3′-OH terminus of RNA chains while expe...
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| Veröffentlicht in: | RNA |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cold Spring Harbor Laboratory Press
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8284320/ https://ncbi.nlm.nih.gov/pubmed/34088850 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.078822.121 |
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