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Structure and two-metal mechanism of a eukaryal nick-sealing RNA ligase

ATP-dependent RNA ligases are agents of RNA repair that join 3′-OH and 5′-PO(4) RNA ends. Naegleria gruberi RNA ligase (NgrRnl) exemplifies a family of RNA nick-sealing enzymes found in bacteria, viruses, and eukarya. Crystal structures of NgrRnl at three discrete steps along the reaction pathway—co...

詳細記述

保存先:
書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Unciuleac, Mihaela-Carmen, Goldgur, Yehuda, Shuman, Stewart
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4653202/
https://ncbi.nlm.nih.gov/pubmed/26512110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1516536112
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