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Structure and two-metal mechanism of a eukaryal nick-sealing RNA ligase
ATP-dependent RNA ligases are agents of RNA repair that join 3′-OH and 5′-PO(4) RNA ends. Naegleria gruberi RNA ligase (NgrRnl) exemplifies a family of RNA nick-sealing enzymes found in bacteria, viruses, and eukarya. Crystal structures of NgrRnl at three discrete steps along the reaction pathway—co...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4653202/ https://ncbi.nlm.nih.gov/pubmed/26512110 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1516536112 |
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