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Shared active site architecture between archaeal PolD and multi-subunit RNA polymerases revealed by X-ray crystallography
Archaeal replicative DNA polymerase D (PolD) constitute an atypical class of DNA polymerases made of a proofreading exonuclease subunit (DP1) and a larger polymerase catalytic subunit (DP2), both with unknown structures. We have determined the crystal structures of Pyrococcus abyssi DP1 and DP2 at 2...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4996933/ https://ncbi.nlm.nih.gov/pubmed/27548043 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12227 |
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