Reduced In Vitro Susceptibility of Streptococcus pyogenes to β-Lactam Antibiotics Associated with Mutations in the pbp2x Gene Is Geographically Widespread

Recently, two related Streptococcus pyogenes strains with reduced susceptibility to ampicillin, amoxicillin, and cefotaxime, antibiotics commonly used to treat S. pyogenes infections, were reported. The two strains had the same nonsynonymous (amino acid-substituting) mutation in the pbp2x gene, enco...

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Dades bibliogràfiques
Publicat a:J Clin Microbiol
Autors principals: Musser, James M., Beres, Stephen B., Zhu, Luchang, Olsen, Randall J., Vuopio, Jaana, Hyyryläinen, Hanne-Leena, Gröndahl-Yli-Hannuksela, Kirsi, Kristinsson, Karl G., Darenberg, Jessica, Henriques-Normark, Birgitta, Hoffmann, Steen, Caugant, Dominque A., Smith, Andrew J., Lindsay, Diane S. J., Boragine, David M., Palzkill, Timothy
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2020
Matèries:
Bacteriology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7098749/
https://ncbi.nlm.nih.gov/pubmed/31996443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.01993-19
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