Reduced In Vitro Susceptibility of Streptococcus pyogenes to β-Lactam Antibiotics Associated with Mutations in the pbp2x Gene Is Geographically Widespread

Recently, two related Streptococcus pyogenes strains with reduced susceptibility to ampicillin, amoxicillin, and cefotaxime, antibiotics commonly used to treat S. pyogenes infections, were reported. The two strains had the same nonsynonymous (amino acid-substituting) mutation in the pbp2x gene, enco...

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Detalles Bibliográficos
Publicado en:J Clin Microbiol
Main Authors: Musser, James M., Beres, Stephen B., Zhu, Luchang, Olsen, Randall J., Vuopio, Jaana, Hyyryläinen, Hanne-Leena, Gröndahl-Yli-Hannuksela, Kirsi, Kristinsson, Karl G., Darenberg, Jessica, Henriques-Normark, Birgitta, Hoffmann, Steen, Caugant, Dominque A., Smith, Andrew J., Lindsay, Diane S. J., Boragine, David M., Palzkill, Timothy
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2020
Assuntos:
Bacteriology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7098749/
https://ncbi.nlm.nih.gov/pubmed/31996443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.01993-19
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