Reduced In Vitro Susceptibility of Streptococcus pyogenes to β-Lactam Antibiotics Associated with Mutations in the pbp2x Gene Is Geographically Widespread

Recently, two related Streptococcus pyogenes strains with reduced susceptibility to ampicillin, amoxicillin, and cefotaxime, antibiotics commonly used to treat S. pyogenes infections, were reported. The two strains had the same nonsynonymous (amino acid-substituting) mutation in the pbp2x gene, enco...

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Detalhes bibliográficos
Publicado no:J Clin Microbiol
Main Authors: Musser, James M., Beres, Stephen B., Zhu, Luchang, Olsen, Randall J., Vuopio, Jaana, Hyyryläinen, Hanne-Leena, Gröndahl-Yli-Hannuksela, Kirsi, Kristinsson, Karl G., Darenberg, Jessica, Henriques-Normark, Birgitta, Hoffmann, Steen, Caugant, Dominque A., Smith, Andrew J., Lindsay, Diane S. J., Boragine, David M., Palzkill, Timothy
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Bacteriology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7098749/
https://ncbi.nlm.nih.gov/pubmed/31996443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.01993-19
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