Exenatide induces frataxin expression and improves mitochondrial function in Friedreich ataxia

Friedreich ataxia is an autosomal recessive neurodegenerative disease associated with a high diabetes prevalence. No treatment is available to prevent or delay disease progression. Friedreich ataxia is caused by intronic GAA trinucleotide repeat expansions in the frataxin-encoding FXN gene that redu...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:JCI Insight
Huvudupphovsmän: Igoillo-Esteve, Mariana, Oliveira, Ana F., Cosentino, Cristina, Fantuzzi, Federica, Demarez, Céline, Toivonen, Sanna, Hu, Amélie, Chintawar, Satyan, Lopes, Miguel, Pachera, Nathalie, Cai, Ying, Abdulkarim, Baroj, Rai, Myriam, Marselli, Lorella, Marchetti, Piero, Tariq, Mohammad, Jonas, Jean-Christophe, Boscolo, Marina, Pandolfo, Massimo, Eizirik, Décio L., Cnop, Miriam
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Clinical Investigation 2020
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7098728/
https://ncbi.nlm.nih.gov/pubmed/31877117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.134221
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk