Exenatide induces frataxin expression and improves mitochondrial function in Friedreich ataxia

Friedreich ataxia is an autosomal recessive neurodegenerative disease associated with a high diabetes prevalence. No treatment is available to prevent or delay disease progression. Friedreich ataxia is caused by intronic GAA trinucleotide repeat expansions in the frataxin-encoding FXN gene that redu...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Igoillo-Esteve, Mariana, Oliveira, Ana F., Cosentino, Cristina, Fantuzzi, Federica, Demarez, Céline, Toivonen, Sanna, Hu, Amélie, Chintawar, Satyan, Lopes, Miguel, Pachera, Nathalie, Cai, Ying, Abdulkarim, Baroj, Rai, Myriam, Marselli, Lorella, Marchetti, Piero, Tariq, Mohammad, Jonas, Jean-Christophe, Boscolo, Marina, Pandolfo, Massimo, Eizirik, Décio L., Cnop, Miriam
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7098728/
https://ncbi.nlm.nih.gov/pubmed/31877117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.134221
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados