Genome-wide Screening Identifies SFMBT1 as an Oncogenic Driver in Cancer with VHL Loss

von Hippel-Lindau (VHL) is a critical tumor suppressor in clear cell renal cell carcinomas (ccRCCs). It is important to identify additional therapeutic targets in ccRCC downstream of VHL loss besides hypoxia inducible factor 2α (HIF2α). By performing a genome-wide screen, we identified Scm-like with...

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Bibliografiset tiedot
Julkaisussa:Mol Cell
Päätekijät: Liu, Xijuan, Simon, Jeremy M., Xie, Haibiao, Hu, Lianxin, Wang, Jun, Zurlo, Giada, Fan, Cheng, Ptacek, Travis S., Herring, Laura, Tan, Xianming, Li, Mingjie, Baldwin, Albert S., Kim, William Y., Wu, Tao, Kirschner, Marc W., Gong, Kan, Zhang, Qing
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2020
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7093231/
https://ncbi.nlm.nih.gov/pubmed/32023483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2020.01.009
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