Prolyl hydroxylase substrate adenylosuccinate lyase is an oncogenic driver in triple negative breast cancer

Protein hydroxylation affects protein stability, activity, and interactome, therefore contributing to various diseases including cancers. However, the transiency of the hydroxylation reaction hinders the identification of hydroxylase substrates. By developing an enzyme-substrate trapping strategy co...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nat Commun
Päätekijät: Zurlo, Giada, Liu, Xijuan, Takada, Mamoru, Fan, Cheng, Simon, Jeremy M., Ptacek, Travis S., Rodriguez, Javier, von Kriegsheim, Alex, Liu, Juan, Locasale, Jason W., Robinson, Adam, Zhang, Jing, Holler, Jessica M., Kim, Baek, Zikánová, Marie, Bierau, Jörgen, Xie, Ling, Chen, Xian, Li, Mingjie, Perou, Charles M., Zhang, Qing
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2019
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6858455/
https://ncbi.nlm.nih.gov/pubmed/31729379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13168-4
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia