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Adenylosuccinate lyase hydroxylation contributes to triple negative breast cancer via the activation of cMYC
Hydroxylation is a post-translational modification affecting protein stability, activity or interactome. We identified adenylosuccinate lyase (ADSL) as a novel hydroxylation substrate in triple negative breast cancer. Hydroxylation affects ADSL enzymatic activity and, therefore, adenosine levels. Ad...
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| Publicado no: | Mol Cell Oncol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7051151/ https://ncbi.nlm.nih.gov/pubmed/32158921 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2019.1707045 |
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