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Genetic variants in RET, ARHGEF3 and CTNNAL1, and relevant interaction networks, contribute to the risk of Hirschsprung disease

Hirschsprung disease (HSCR), the most common enteric neuropathy, stands as a model for complex genetic disorders. It has recently been demonstrated that both ARHGEF3 and CTNNAL1 map to the RET-dependent HSCR susceptibility loci. We therefore sought to explore whether genetic variants within RET, ARH...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Aging (Albany NY)
Egile Nagusiak: Wang, Yang, Jiang, Qian, Cai, Hao, Xu, Ze, Wu, Wenjie, Gu, Beilin, Li, Long, Cai, Wei
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Impact Journals 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7093166/
https://ncbi.nlm.nih.gov/pubmed/32139661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102891
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