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Copy Number Variants in Candidate Genes Are Genetic Modifiers of Hirschsprung Disease

Hirschsprung disease (HSCR) is a neurocristopathy characterized by absence of intramural ganglion cells along variable lengths of the gastrointestinal tract. The HSCR phenotype is highly variable with respect to gender, length of aganglionosis, familiality and the presence of additional anomalies. B...

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Bibliografiske detaljer
Main Authors: Jiang, Qian, Ho, Yen-Yi, Hao, Li, Nichols Berrios, Courtney, Chakravarti, Aravinda
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119685/
https://ncbi.nlm.nih.gov/pubmed/21712996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021219
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