A novel siRNA validation system for functional screening and identification of effective RNAi probes in mammalian cells

Small interfering RNAs (siRNAs) have become the most powerful and widely used gene silencing reagents for reverse functional genomics and molecular therapeutics. The key challenge for achieving effective gene silencing in particular for the purpose of the therapeutics is primarily dependent on the e...

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發表在:Biochem Biophys Res Commun
Main Authors: Hung, Chuan-Fu, Lu, Kuang-Chu, Cheng, Tsung-Lin, Wu, Ren-Huang, Huang, Lin-Ya, Teng, Chiao-Fang, Chang, Wen-Tsan
格式: Artigo
語言:Inglês
出版: Elsevier Inc. 2006
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7092908/
https://ncbi.nlm.nih.gov/pubmed/16793020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2006.05.164
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