A novel siRNA validation system for functional screening and identification of effective RNAi probes in mammalian cells

Small interfering RNAs (siRNAs) have become the most powerful and widely used gene silencing reagents for reverse functional genomics and molecular therapeutics. The key challenge for achieving effective gene silencing in particular for the purpose of the therapeutics is primarily dependent on the e...

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Bibliographic Details
Published in:Biochem Biophys Res Commun
Main Authors: Hung, Chuan-Fu, Lu, Kuang-Chu, Cheng, Tsung-Lin, Wu, Ren-Huang, Huang, Lin-Ya, Teng, Chiao-Fang, Chang, Wen-Tsan
Format: Artigo
Language:Inglês
Published: Elsevier Inc. 2006
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7092908/
https://ncbi.nlm.nih.gov/pubmed/16793020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2006.05.164
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