A novel siRNA validation system for functional screening and identification of effective RNAi probes in mammalian cells

Small interfering RNAs (siRNAs) have become the most powerful and widely used gene silencing reagents for reverse functional genomics and molecular therapeutics. The key challenge for achieving effective gene silencing in particular for the purpose of the therapeutics is primarily dependent on the e...

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Vydáno v:Biochem Biophys Res Commun
Hlavní autoři: Hung, Chuan-Fu, Lu, Kuang-Chu, Cheng, Tsung-Lin, Wu, Ren-Huang, Huang, Lin-Ya, Teng, Chiao-Fang, Chang, Wen-Tsan
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier Inc. 2006
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7092908/
https://ncbi.nlm.nih.gov/pubmed/16793020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2006.05.164
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