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Probing arrestin function using intramolecular FlAsH-BRET biosensors

Information contained in the structure of extracellular ligands is transmitted across the cell membrane through allosterically induced changes in G protein-coupled receptor (GPCR) conformation that occur upon ligand binding. These changes, in turn, are imprinted upon intracellular effectors like arr...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Methods Mol Biol
Main Authors: Strungs, Erik G., Luttrell, Louis M., Lee, Mi-Hye
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7092779/
https://ncbi.nlm.nih.gov/pubmed/30919362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-9158-7_19
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