Distinct Conformational Dynamics of Three G Protein-Coupled Receptors Measured Using FlAsH-BRET Biosensors

A number of studies have profiled G protein-coupled receptor (GPCR) conformation using fluorescent biaresenical hairpin binders (FlAsH) as acceptors for BRET or FRET. These conformation-sensitive biosensors allow reporting of movements occurring on the intracellular surface of a receptor to investig...

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Detalles Bibliográficos
Publicado en:Front Endocrinol (Lausanne)
Main Authors: Bourque, Kyla, Pétrin, Darlaine, Sleno, Rory, Devost, Dominic, Zhang, Alice, Hébert, Terence E.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2017
Assuntos:
Endocrinology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5383666/
https://ncbi.nlm.nih.gov/pubmed/28439254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2017.00061
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