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High-resolution Repli-Seq defines the temporal choreography of initiation, elongation and termination of replication in mammalian cells

BACKGROUND: DNA replication in mammalian cells occurs in a defined temporal order during S phase, known as the replication timing (RT) programme. Replication timing is developmentally regulated and correlated with chromatin conformation and local transcriptional potential. Here, we present RT profil...

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Bibliografske podrobnosti
izdano v:Genome Biol
Main Authors: Zhao, Peiyao A., Sasaki, Takayo, Gilbert, David M.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7092589/
https://ncbi.nlm.nih.gov/pubmed/32209126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-020-01983-8
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