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Multi-peaked adaptive landscape for chikungunya virus evolution predicts continued fitness optimization in Aedes albopictus mosquitoes

Host species-specific fitness landscapes largely determine the outcome of host switching during pathogen emergence. Using chikungunya virus (CHIKV) to study adaptation to a mosquito vector, we evaluated mutations associated with recently evolved sub-lineages. Multiple Aedes albopictus-adaptive fitne...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Nat Commun
Main Authors: Tsetsarkin, Konstantin A., Chen, Rubing, Yun, Ruimei, Rossi, Shannan L., Plante, Kenneth S., Guerbois, Mathilde, Forrester, Naomi, Perng, Guey Chuen, Sreekumar, Easwaran, Leal, Grace, Huang, Jing, Mukhopadhyay, Suchetana, Weaver, Scott C.
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group UK 2014
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7091890/
https://ncbi.nlm.nih.gov/pubmed/24933611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5084
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