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Chikungunya virus adaptation to Aedes albopictus mosquitoes does not correlate with acquisition of cholesterol dependence or decreased pH threshold for fusion reaction

BACKGROUND: Chikungunya virus (CHIKV) is a mosquito transmitted alphavirus that recently caused several large scale outbreaks/epidemics of arthritic disease in tropics of Africa, Indian Ocean basin and South-East Asia. This re-emergence event was facilitated by genetic adaptation (E1-A226V substitut...

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Detalhes bibliográficos
Main Authors: Tsetsarkin, Konstantin A, McGee, Charles E, Higgs, Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3162544/
https://ncbi.nlm.nih.gov/pubmed/21801412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-8-376
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