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Epistatic Roles of E2 Glycoprotein Mutations in Adaption of Chikungunya Virus to Aedes Albopictus and Ae. Aegypti Mosquitoes

Between 2005 and 2007 Chikungunya virus (CHIKV) caused its largest outbreak/epidemic in documented history. An unusual feature of this epidemic is the involvement of Ae. albopictus as a principal vector. Previously we have demonstrated that a single mutation E1-A226V significantly changed the abilit...

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Detalhes bibliográficos
Main Authors: Tsetsarkin, Konstantin A., McGee, Charles E., Volk, Sara M., Vanlandingham, Dana L., Weaver, Scott C., Higgs, Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2729410/
https://ncbi.nlm.nih.gov/pubmed/19718263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006835
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