Multi-peaked adaptive landscape for chikungunya virus evolution predicts continued fitness optimization in Aedes albopictus mosquitoes

Host species-specific fitness landscapes largely determine the outcome of host switching during pathogen emergence. Using chikungunya virus (CHIKV) to study adaptation to a mosquito vector, we evaluated mutations associated with recently evolved sub-lineages. Multiple Aedes albopictus-adaptive fitne...

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Bibliografski detalji
Izdano u:Nat Commun
Glavni autori: Tsetsarkin, Konstantin A., Chen, Rubing, Yun, Ruimei, Rossi, Shannan L., Plante, Kenneth S., Guerbois, Mathilde, Forrester, Naomi, Perng, Guey Chuen, Sreekumar, Easwaran, Leal, Grace, Huang, Jing, Mukhopadhyay, Suchetana, Weaver, Scott C.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2014
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7091890/
https://ncbi.nlm.nih.gov/pubmed/24933611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5084
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