Multi-peaked adaptive landscape for chikungunya virus evolution predicts continued fitness optimization in Aedes albopictus mosquitoes

Host species-specific fitness landscapes largely determine the outcome of host switching during pathogen emergence. Using chikungunya virus (CHIKV) to study adaptation to a mosquito vector, we evaluated mutations associated with recently evolved sub-lineages. Multiple Aedes albopictus-adaptive fitne...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Tsetsarkin, Konstantin A., Chen, Rubing, Yun, Ruimei, Rossi, Shannan L., Plante, Kenneth S., Guerbois, Mathilde, Forrester, Naomi, Perng, Guey Chuen, Sreekumar, Easwaran, Leal, Grace, Huang, Jing, Mukhopadhyay, Suchetana, Weaver, Scott C.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7091890/
https://ncbi.nlm.nih.gov/pubmed/24933611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5084
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