Improved antibiotic-free plasmid vector design by incorporation of transient expression enhancers

Methods to improve plasmid-mediated transgene expression are needed for gene medicine and gene vaccination applications. To maintain a low risk of insertional mutagenesis-mediated gene activation, expression-augmenting sequences would ideally function to improve transgene expression from transiently...

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Detalhes bibliográficos
Publicado no:Gene Ther
Main Authors: Luke, J M, Vincent, J M, Du, S X, Gerdemann, U, Leen, A M, Whalen, R G, Hodgson, C P, Williams, J A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7091570/
https://ncbi.nlm.nih.gov/pubmed/21107439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2010.149
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