A transient three-plasmid expression system for the production of high titer retroviral vectors.

We have constructed a series of MLV-based retroviral vectors and packaging components expressed from the CMV promoter and carried on plasmids containing SV40 origins of replication. These two features greatly enhanced retroviral gene expression when introduced into cell lines carrying the SV40 large...

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Detalhes bibliográficos
Main Authors: Soneoka, Y, Cannon, P M, Ramsdale, E E, Griffiths, J C, Romano, G, Kingsman, S M, Kingsman, A J
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC306730/
https://ncbi.nlm.nih.gov/pubmed/7899083
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