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Transduction Efficiency of Pantropic Retroviral Vectors Is Controlled by the Envelope Plasmid to Vector Plasmid Ratio

Pantropic retroviral vectors pseudotyped with vesicular stomatitis virus envelope G protein (VSV-G) are typically produced by transient transfection of the VSV-G expression plasmid because constitutive expression of VSV-G is cytotoxic. To produce pantropic vectors, the VSV-G expression plasmid and t...

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Detalhes bibliográficos
Main Authors: Chen, Yong, Miller, William M., Aiyar, Ashok
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913131/
https://ncbi.nlm.nih.gov/pubmed/15903266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bp049865x
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