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A general method for the generation of high-titer, pantropic retroviral vectors: highly efficient infection of primary hepatocytes.

Retroviral vectors have been central components in many studies leading to human gene therapy. However, the generally low titers and inefficient infectivity of retroviral vectors in human cells have limited their use. We previously reported that the G protein of vesicular stomatitis virus can serve...

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Hlavní autoři: Yee, J K, Miyanohara, A, LaPorte, P, Bouic, K, Burns, J C, Friedmann, T
Médium: Artigo
Jazyk:Inglês
Vydáno: 1994
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC44853/
https://ncbi.nlm.nih.gov/pubmed/7937806
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