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Split-Intron Retroviral Vectors: Enhanced Expression with Improved Safety

The inclusion of retrovirus-derived introns within retrovirus-based expression vectors leads to a fraction of the resulting transcripts being spliced. Such splicing has been shown to markedly improve expression (W. J. Krall et al., Gene Ther. 3:37–48, 1996). One way to improve upon this still furthe...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ismail, Said I., Kingsman, Susan M., Kingsman, Alan J., Uden, Mark
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2000
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC111718/
https://ncbi.nlm.nih.gov/pubmed/10666267
Tagiau: Ychwanegu Tag
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