Split-Intron Retroviral Vectors: Enhanced Expression with Improved Safety
The inclusion of retrovirus-derived introns within retrovirus-based expression vectors leads to a fraction of the resulting transcripts being spliced. Such splicing has been shown to markedly improve expression (W. J. Krall et al., Gene Ther. 3:37–48, 1996). One way to improve upon this still furthe...
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| Publicado no: | J Virol |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111718/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10666267/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.5.2365-2371.2000 |
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