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Minimal Requirement for a Lentivirus Vector Based on Human Immunodeficiency Virus Type 1

The use of human immunodeficiency virus vectors for gene therapy is hampered by concern over their safety. This concern might be ameliorated, in part, if the viral accessory genes and proteins could be eliminated from the vector genomes and particles. Here we describe a minimal vector system that is...

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Detalhes bibliográficos
Main Authors: Kim, V. Narry, Mitrophanous, Kyriacos, Kingsman, Susan M., Kingsman, Alan J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC109441/
https://ncbi.nlm.nih.gov/pubmed/9420292
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