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Minimal Requirement for a Lentivirus Vector Based on Human Immunodeficiency Virus Type 1

The use of human immunodeficiency virus vectors for gene therapy is hampered by concern over their safety. This concern might be ameliorated, in part, if the viral accessory genes and proteins could be eliminated from the vector genomes and particles. Here we describe a minimal vector system that is...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kim, V. Narry, Mitrophanous, Kyriacos, Kingsman, Susan M., Kingsman, Alan J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 1998
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC109441/
https://ncbi.nlm.nih.gov/pubmed/9420292
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