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Plasmid DNA Vaccine vector design: impact on efficacy, safety and upstream production
Critical molecular and cellular biological factors impacting design of licensable DNA vaccine vectors that combine high yield and integrity during bacterial production with increased expression in mammalian cells are reviewed. Food and Drug Administration (FDA), World Health Organization (WHO) and E...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2693335/ https://ncbi.nlm.nih.gov/pubmed/19233255 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biotechadv.2009.02.003 |
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