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Safety and efficacy of DNA vaccines: Plasmids vs. minicircles

While DNA vaccination using plasmid vectors is highly attractive, there is a need for further vector optimization regarding safety, stability, and efficiency. In this commentary, we review the minicircle vector (MC), which is an entity devoid of plasmid bacterial sequences, as an alternative to the...

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Detalhes bibliográficos
Publicado no:Hum Vaccin Immunother
Main Authors: Stenler, Sofia, Blomberg, Pontus, Smith, CI Edvard
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4896608/
https://ncbi.nlm.nih.gov/pubmed/24553064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.28077
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