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Safety and efficacy of DNA vaccines: Plasmids vs. minicircles
While DNA vaccination using plasmid vectors is highly attractive, there is a need for further vector optimization regarding safety, stability, and efficiency. In this commentary, we review the minicircle vector (MC), which is an entity devoid of plasmid bacterial sequences, as an alternative to the...
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Publicado no: | Hum Vaccin Immunother |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Taylor & Francis
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4896608/ https://ncbi.nlm.nih.gov/pubmed/24553064 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.28077 |
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