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Safety and efficacy of DNA vaccines: Plasmids vs. minicircles

While DNA vaccination using plasmid vectors is highly attractive, there is a need for further vector optimization regarding safety, stability, and efficiency. In this commentary, we review the minicircle vector (MC), which is an entity devoid of plasmid bacterial sequences, as an alternative to the...

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Bibliografiska uppgifter
I publikationen:Hum Vaccin Immunother
Huvudupphovsmän: Stenler, Sofia, Blomberg, Pontus, Smith, CI Edvard
Materialtyp: Artigo
Språk:Inglês
Publicerad: Taylor & Francis 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4896608/
https://ncbi.nlm.nih.gov/pubmed/24553064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.28077
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