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Generic plasmid DNA production platform incorporating low metabolic burden seed-stock and fed-batch fermentation processes

DNA vaccines have tremendous potential for rapid deployment in pandemic applications, wherein a new antigen is ‘plugged’ into a validated vector, and rapidly produced in a validated, fermentation - purification process. For this application, it is essential that the vector and fermentation process f...

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Hlavní autoři: Williams, James A, Luke, Jeremy, Langtry, Sarah, Anderson, Sheryl, Hodgson, Clague P, Carnes, Aaron E
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2735187/
https://ncbi.nlm.nih.gov/pubmed/19408315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.22347
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