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Regioselective Single-Electron Tsuji-Trost Reaction of Allylic Alcohols: A Photoredox/Nickel Dual Catalytic Approach

A radical-mediated functionalization of allyl alcohol-derived partners with a variety of alkyl 1,4-dihydropyridines via photoredox/nickel dual catalysis is described. This transformation transpires with high linear and E-selectivity, avoiding the requirement of harsh conditions (e.g., strong base, e...

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Détails bibliographiques
Publié dans:Org Lett
Auteurs principaux: Wang, Zheng-Jun, Zheng, Shuai, Romero, Eugénie, Matsui, Jennifer K., Molander, Gary A.
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7091330/
https://ncbi.nlm.nih.gov/pubmed/31390217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.9b02473
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