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Catalytic Asymmetric Synthesis of Diketopiperazines by Intramolecular Tsuji–Trost Allylation
[Image: see text] We report the intramolecular Tsuji–Trost reaction of Ugi adducts to give spiro-diketopiperazines in high yield and with high enantioselectivity. This approach allows the catalytic asymmetric construction of a broad range of these medicinally important heterocycles under mild condit...
Tallennettuna:
| Julkaisussa: | J Org Chem |
|---|---|
| Päätekijät: | , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Chemical
Society
2019
|
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6760471/ https://ncbi.nlm.nih.gov/pubmed/31446758 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.9b01994 |
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