Metabolic Engineering of Saccharomyces cerevisiae for Enhanced Dihydroartemisinic Acid Production

Direct bioproduction of DHAA (dihydroartemisinic acid) rather than AA (artemisinic acid), as suggested by previous work would decrease the cost of semi-biosynthesis artemisinin by eliminating the step of initial hydrogenation of AA. The major challenge in microbial production of DHAA is how to effic...

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Bibliographic Details
Published in:Front Bioeng Biotechnol
Main Authors: Zeng, Bo-Xuan, Yao, Ming-Dong, Wang, Ying, Xiao, Wen-Hai, Yuan, Ying-Jin
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Bioengineering and Biotechnology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7090239/
https://ncbi.nlm.nih.gov/pubmed/32258005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2020.00152
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