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Metabolic Engineering of Saccharomyces cerevisiae for Enhanced Dihydroartemisinic Acid Production

Direct bioproduction of DHAA (dihydroartemisinic acid) rather than AA (artemisinic acid), as suggested by previous work would decrease the cost of semi-biosynthesis artemisinin by eliminating the step of initial hydrogenation of AA. The major challenge in microbial production of DHAA is how to effic...

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Bibliographische Detailangaben
Veröffentlicht in:Front Bioeng Biotechnol
Hauptverfasser: Zeng, Bo-Xuan, Yao, Ming-Dong, Wang, Ying, Xiao, Wen-Hai, Yuan, Ying-Jin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7090239/
https://ncbi.nlm.nih.gov/pubmed/32258005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2020.00152
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