Metabolic Engineering of Saccharomyces cerevisiae for Enhanced Dihydroartemisinic Acid Production

Direct bioproduction of DHAA (dihydroartemisinic acid) rather than AA (artemisinic acid), as suggested by previous work would decrease the cost of semi-biosynthesis artemisinin by eliminating the step of initial hydrogenation of AA. The major challenge in microbial production of DHAA is how to effic...

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Vydáno v:Front Bioeng Biotechnol
Hlavní autoři: Zeng, Bo-Xuan, Yao, Ming-Dong, Wang, Ying, Xiao, Wen-Hai, Yuan, Ying-Jin
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
Bioengineering and Biotechnology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7090239/
https://ncbi.nlm.nih.gov/pubmed/32258005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2020.00152
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