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Metabolic Engineering of Saccharomyces cerevisiae for Enhanced Dihydroartemisinic Acid Production

Direct bioproduction of DHAA (dihydroartemisinic acid) rather than AA (artemisinic acid), as suggested by previous work would decrease the cost of semi-biosynthesis artemisinin by eliminating the step of initial hydrogenation of AA. The major challenge in microbial production of DHAA is how to effic...

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Dettagli Bibliografici
Pubblicato in:Front Bioeng Biotechnol
Autori principali: Zeng, Bo-Xuan, Yao, Ming-Dong, Wang, Ying, Xiao, Wen-Hai, Yuan, Ying-Jin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7090239/
https://ncbi.nlm.nih.gov/pubmed/32258005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2020.00152
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