Metabolic Engineering of Glycerol Production in Saccharomyces cerevisiae

Inactivation of TPI1, the Saccharomyces cerevisiae structural gene encoding triose phosphate isomerase, completely eliminates growth on glucose as the sole carbon source. In tpi1-null mutants, intracellular accumulation of dihydroxyacetone phosphate might be prevented if the cytosolic NADH generated...

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Autores principales: Overkamp, Karin M., Bakker, Barbara M., Kötter, Peter, Luttik, Marijke A. H., van Dijken, Johannes P., Pronk, Jack T.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2002
Materias:
Physiology and Biotechnology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC123913/
https://ncbi.nlm.nih.gov/pubmed/12039737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.68.6.2814-2821.2002
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